. 2021 May;10(5):2019–2026. doi: 10.21037/tau-20-1378

Table 2. Association of clinical and pathological characteristics with the expression of miR-145.

Characteristics	Subgroup	miR-145 level	P value
Histological subtype	Associated with HPV*	−1.43±−0.65	0.024
Histological subtype	Not HPV associated*	−1.43±−0.65	0.024
Tumor size	≤0.1–5.0 cm	−0.99±−1.10	0.73
Tumor size	≥5.1–10 cm	−0.99±−1.10	0.73
Histological grade	I–II	−0.93±−0.95	0.93
Histological grade	III	−0.93±−0.95	0.93
Perineural invasion	Negative	1.16±0.5	0.033
Perineural invasion	Positive	1.16±0.5	0.033
Lymphatic invasion	Positive	−0.98±−0.81	0.61
Lymphatic invasion	Negative	−0.98±−0.81	0.61
Primary tumor (pT)	pT1-pT2	1.15±0.63	0.09
Primary tumor (pT)	pT3	1.15±0.63	0.09
Metastasis	Negative	−0.88±−1.09	0.57
Metastasis	Positive	−0.88±−1.09	0.57

*Associated with HPV: Warty and Basaloid; *Not HPV associated: usual. HPV, human papillomavirus.