Figure 1.

Immunohistochemical expression of sLe^x and MUC1/EMA in breast IMPC and IDC-NOS. (A) IMPC consists of tumor cell clusters of epithelial cells surrounded by gaps [hematoxylin and eosin (HE) staining]. (B) Representative microphotographs of IDC-NOS (HE). Immunohistochemistry confirming the expression of sLe^x on the cytomembranes in IMPC cell clusters (C) and IDC-NOS cells (D). The expression of sLe^x within the cytoplasm in IMPC cell clusters (E) and IDC-NOS cells (F). EMA immunostaining showing the typical polarity reversal growth pattern of IMPC (G) and the normal pattern in IDC-NOS tumor cells (H) (200×, 400×, indicated by the red arrow).