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Comparison of acrolein-DNA adducts with previous studies.
| α-OH-Acr-dGuo (1) adducts/109 nucleotides |
γ-OH-Acr-dGuo (2) adducts/109 nucleotides |
|||
|---|---|---|---|---|
| DNA Sample Type | Smokers | Non-smokers | Smokers | Non-smokers |
| Lung30 | 8.6 ± 2.7 | 10.3 ± 4.7 | 19.9 ± 14.3 | 14.7 ± 6.4 |
| Leukocyte28 | ND | ND | 7.0 ± 2.5 | 9.7 ± 5.5 |
| Oral rinse | 12.1 ± 17.9 | 1.85 ± 2.08 | 163 ± 227 | 5.95 ± 4.23 |
| Cytobrush | 1.8 ± 13.1 | ND | 259 ± 540 | 7.37 ± 5.09 |
