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. 2021 Jun 7;21:298. doi: 10.1186/s12935-021-01983-z

Fig. 1.

Fig. 1

Conceptual schema of the generation and activation of NK cells. In the present study, RAS/MAPK, PI3K/AKT, JAK/STAT pathways (involved in NK cells differentiation and activation) and TGF-β pathway (involved in NK cells dysfunction) were induced and inhibited respectively