Table 7.

Association results between metabolic syndrome traits and MT-CN polygenic risk score in 357656 UK Biobank samples. β refers to the regression coefficient of MT-CN in a linear regression of cell type onto MT-CN PRS and other covariates (see Methods). Bolded results are significant below a nominal α = 0.05. The weight phenotype tested was that which was measured at the time of impedance measurement.

Trait	Without platelet and neutrophil adjustment			With platelet and neutrophil adjustment
	β	SE	P	β	SE	P
Type 2 diabetes	− 0.1681	0.0826	0.0419	− 0.1467	0.0844	0.0823
BMI	− 0.0372	0.0175	0.0331	− 0.0233	0.0175	0.1836
Fat mass	− 0.0452	0.0176	0.0100	− 0.0318	0.0177	0.0716
C-reactive protein	− 0.0015	0.0178	0.9305	0.0206	0.0171	0.2291
HDL	0.0573	0.0187	0.0021	0.0416	0.0187	0.0262
Total triglycerides	− 0.0500	0.0176	0.0046	− 0.0330	0.0175	0.0603
Weight	− 0.0359	0.0176	0.0414	− 0.0218	0.0178	0.2189