TABLE 1.
Demographic characteristics and clinical features of GACRS and CAMP subjects
| GACRS Study | CAMP study | p-value | |
|---|---|---|---|
| Subjects n | 894 | 286 | |
| Age years | 9.28 ± 1.86 | 8.90 ± 2.16 | 7.59×10−3 |
| Male sex | 528 (59.06) | 193 (67.48) | 0.0134 |
| BMI kg/m2 | 18.45 ± 3.92 | 18.24 ± 3.28 | 0.357 |
| Spirometric measures | |||
| FEV1 L | 1.80 ± 0.52 | 1.65 ± 0.47 | 1.03×10−5 |
| FEV1 % pred | 98.87 ± 16.84 | 92.82 ± 13.40 | 1.17×10−9 |
| FEV1/FVC % | 84.36 ± 7.79 | 79.69 ± 8.07 | 2.20×10−16 |
| FEV1/FVC % pred | 94.87 ± 8.70 | 90.36 ± 8.94 | 5.36×10−13 |
| Bronchodilator Response as % of baseline FEV1 | 5.58 ± 10.20 | 10.86 ± 9.49 | 7.50×10−15 |
| Log10 dose-response slope from saline | 1.15 ± 0.54 | 0.97 ± 0.47 | 1.92×10−7 |
| Blood tests | |||
| Total serum IgE IU·mL−1 | 725.26 ± 898.96 | 444.56 ± 797.47 | 7.89×10−7 |
| Eosinophil, count·mm−2 | 553.84 ± 403.93 | 511.96 ± 425.43 | 0.148 |
| Positive skin tests to allergens | 3.08 ± 1.82 | 5.56 ± 4.20 | 2.20×10−16 |
Data are presented as mean±SD or n (%), unless otherwise indicated. GACRS: Genetic Epidemiology of Asthma in Costa Rica Study; CAMP: Childhood Asthma Management Program; BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity.