Figure 13.

Effect of baicalin combined with miR-200b-3p mimic on the FSTL1 signaling pathway and inflammation in LPS-induced alveolar type II epithelial cells. The A549 cells were transfected with miR-200b-3p mimic in the presence of 1 mg/l LPS and 50 μM baicalin for 24 h. FSTL1, p-ERK1/2, p-JNK1, NF-κB65, and p-IκB-α protein expression levels were measured by Western blot. IL-6, IL-1β, and TNF-α in A549 cells were measured by ELISA. The data from three independent experiments is presented as the mean ± SEM. *P < 0.05 versus the control group. #P < 0.05 versus the only LPS group. ▲P < 0.05 versus the mimic group.