Table 3.

Variables associated with ME extent in multivariate linear regression model

Variable	β	SE	95% CI for β	P value	Score (0, 1)
Pathologic grade	0.513	0.136	0.232–0.794	0.001
Grade III					0
Grade IV					1
SVZ contact	0.380	0.124	0.125–0.635	0.005
No					0
Yes					1
Molecular markers
MGMT methylation status	0.439	0.129	0.171–0.706	0.002
Unmethylated					0
Methylated					1
IDH mutation status	0.320	0.141	0.028–0.611	0.033
Mutated					0
Wild type					1
1p/19q co-deletion status	0.333	0.120	0.084–0.581	0.011
Co-deleted					0
Non-co-deleted					1

ME microscopic extension; β regression coefficient; SE standard error; CI confidence interval; SVZ subventricular zone; MGMT O⁶-methylguanine-DNA-methyltransferase; IDH isocitrate dehydrogenase; 1p/19q co-deletion the co-deletion of chromosome arms 1p and 19q