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. 2021 Jun 8;22:309. doi: 10.1186/s12859-021-04150-3

Fig. 8.

Fig. 8

Results obtained on the MCA datasets. a Boxplot showing the ARI values achieved by CCA, ComBat, PCA, MMDVAE followed by Harmony with dimension (256, 64), PCA followed by BBKNN, and PCA followed by Harmony. b Boxplot showing the ARI values achieved by the best AE for each of the tested dimension (HL) of the hidden layer (H neurons) and latent space (L neurons). c UMAP visualisation of the cell-type manually annotated in the original paper. d UMAP visualisation of clusters identified by the Leiden algorithm using the resolution corresponding by the best ARI achieved by MMDVAE followed by Harmony. p-value 0.0001 (****); 0.0001<p-value 0.001 (***); 0.001<p-value 0.01 (**); 0.01<p-value 0.05 (*); p-value >0.05 (ns)