Table 4.
α-glucosidase and α-amylase inhibitory potential of different plant extracts
Enzymes | Sample | Concentration | ||||
---|---|---|---|---|---|---|
25 μg/mL | 50 μg/mL | 100 μg/mL | 200 μg/mL | 400 μg/mL | ||
% inhibition | ||||||
α-amylase | APDW | 17.83 ± 0.19** | 26.22 ± 0.34** | 29.05 ± 0.33** | 32.03 ± 0.66** | 37.43 ± 0.65** |
APM | 13.39 ± 0.17*** | 17.61 ± 0.24*** | 17.93 ± 0.31*** | 23.81 ± 0.39*** | 29.31 ± 0.48*** | |
APE | 22.82 ± 0.21* | 31.08 ± 0.28* | 37.83 ± 0.29* | 51.26 ± 0.82* | 55.38 ± 0.73* | |
APEA | 12.37 ± 0.18*** | 17.92 ± 0.19*** | 21.28 ± 0.22*** | 22.71 ± 0.30*** | 27.23 ± 0.41*** | |
+ control | 27.78 ± 0.66 | 44.87 ± 0.93 | 59.43 ± 1.09 | 73.20 ± 1.51 | 89.40 ± 1.24 | |
α-glucocidase | APDW | 14.94 ± 0.21* | 20.61 ± 0.19* | 22.91 ± 0.19** | 30.51 ± 0.44* | 34.14 ± 0.44** |
APM | 11.93 ± 0.20*** | 16.72 ± 0.17** | 20.17 ± 0.15** | 20.52 ± 0.29** | 24.63 ± 0.32*** | |
APE | 16.77 ± 0.34* | 22.82 ± 0.21* | 30.19 ± 0.43* | 33.61 ± 0.31* | 47.23 ± 0.41* | |
APEA | 9.06 ± 0.11*** | 14.98 ± 0.18** | 16.28 ± 0.21*** | 20.75 ± 0.27** | 23.71 ± 0.31*** | |
+ control | 27.32 ± 0.73 | 33.4 ± 1.27 | 53.45 ± 1.11 | 65.98 ± 1.67 | 84.34 ± 1.92 |
Star *–*** represent; *** highly significant, ** slightly significant and * non-significant difference from the control at P < 0.05 by one-way ANOVA in the column. Values are mean ± SD of triplicate. Where APDW, APM, APE and APEA stands for Distilled water, Methanol, Ethanol and Ethyl acetate extracts, respectively