Table 7.

Cytotoxic potential of Aquilegia pubiflora plant extracts against the promastigote and amastigote forms of Leishmania tropica (KWH23)

L. tropica	Sample		Concentration
		25 μg/mL	50 μg/mL	100 μg/mL	200 μg/mL	400 μg/mL	+ control	IC50
Promastigote	APDW	16.7 ± 0.40***	21.3 ± 0.61**	26.4 ± 0.74**	40.7 ± 0.86*	44.1 ± 1.1*	73.1 ± 1.3	443
	APM	14.2 ± 0.51***	24.8 ± 0.63***	31.6 ± 0.70**	41.3 ± 0.91*	47 ± 0.9*	78.8 ± 1.7	410
	APE	20 ± 0.52***	24.5 ± 0.56***	37.2 ± 0.79**	45.3 ± 0.82*	52 ± 1.2*	75.2 ± 1.2	376
	APEA	17.1 ± 0.51***	28.1 ± 0.50**	35.8 ± 0.81**	40.4 ± 0.73*	46.4 ± 0.81*	75.4 ± 1.1	471
Amastigote	APDW	19.4 ± 0.53***	32.8 ± 0.97**	28.9 ± 0.72***	39.6 ± 0.61*	47.4 ± 0.82*	78.7 ± 1.6	464
	APM	19.9 ± 0.63***	26.9 ± 0.41***	32.5 ± 0.86**	41.1 ± 0.69*	51 ± 0.9*	78.1 ± 1.6	381
	APE	20.1 ± 0.64***	31.1 ± 0.69***	44.6 ± 1.1**	51.1 ± 0.83*	59 ± 1.1*	73.9 ± 1.5	344
	APEA	21.4 ± 0.44***	33.8 ± 0.55**	37.8 ± 0.78**	42.3 ± 0.78*	49.1 ± 0.71*	74.9 ± 1.1	425

Star *–*** represent; *** highly significant, ** slightly significant and * non-significant difference from control at P < 0.05 by one-way ANOVA in the column. Values are mean ± SD of triplicate. Where AP_DW, AP_M, AP_E and AP_EA stands for Distilled water, Methanol, Ethanol and Ethyl acetate extracts, respectively