Table 1.
Sample characteristics
| Samples for WGBS* TAD† (n = 6) Controls (n = 6) |
Samples for replication TAD (n = 6) Controls (n = 4) |
|||
|---|---|---|---|---|
| Age, years | 45.3 ± 11.6 | 42.8 ± 5.8‡ | 41.8 ± 8.0 | 36.5 ± 15.2§ |
| Gender, male: female | 5:1 | 6:0 | 5:1 | 3:1 |
| Stanford classification | ||||
| Type A | 6 (100%) | – | 6 (100%) | – |
| Type B | 0 | – | 0 | – |
| Dissection staging | ||||
| Acute phase | 6 (100%) | – | 6 (100%) | – |
| Chronic phase | 0 | – | 0 | – |
| Arteritis | 0 | 0 | 0 | 0 |
| Bicuspid aortic valve | 0 | 0 | 0 | 0 |
| Family history of aortic diseases | 0 | 0 | 0 | 0 |
| Rupture | 0 | – | 0 | – |
| Maximal aortic diameter (mm) | 5.2 ± 1.5 | – | 5.7 ± 3.3 | – |
| Emergent operation | 6 (100%) | – | 6 (100%) | – |
| Elective operation | 0 | – | 0 | – |
*WGBS whole genome bisulfite sequencing
†TAD thoracic aortic dissection
‡P value = 0.646
§P value = 0.497