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. Author manuscript; available in PMC: 2021 Jun 8.
Published in final edited form as: Isr J Chem. 2019 Oct 10;60(3-4):207–218. doi: 10.1002/ijch.201900085

Figure 10.

Figure 10.

Equatorial and axial diastereomers are produced as a separable mixture upon photoisomerization of 5-hydroxy-cis-cyclooctene. These dienophiles have been widely used for applications in bioorthogonal chemistry.