Table 1.
Baseline characteristics of the study participants
Variable | Taurine (n = 22) | Control (n = 22) | p-value |
---|---|---|---|
Age (year) | 33.3 ± 13.4 | 32.4 ± 11.4 | 0.80 |
Gender (N [%]) | 0.99 | ||
Male | 17 (77.3) | 18 (81.8) | |
Female | 5 (22.7) | 4 (18.2) | |
Weight (kg) | 74.1 ± 11.72 | 74.3 ± 8.61 | 0.96 |
BMI (kg/ m2) | 25.3 ± 3.2 | 25.2 ± 2.5 | 0.85 |
Cause of TBI (N [%]) | 0.51 | ||
Accident | 20 (90.9) | 20 (90.9) | |
Fall | 1 (4.5) | 2 (9.1) | |
Gun shut | 1 (4.5) | 0 (0) | |
Glasgow Coma Scale | 7 (7, 7) | 7 (7, 8) | 0.07 |
Type of TBI based on CT scan findings (N [%]) | 0.79 | ||
Diffuse axonal injury | 12 (54.5) | 12 (54.5) | |
Extradural hemorrhage | 3 (13.6) | 2 (9.1) | |
Subarachnoid hemorrhage | 2 (9.1) | 3 (13.6) | |
Subdural hematoma | 4 (18.2) | 4 (18.2) | |
Intraventricular hemorrhage | 0 (0) | 1 (4.5) | |
Intracerebral hemorrhage | 1 (4.5) | 0 (0) | |
Surgical procedures | 0.99 | ||
Craniotomy | 10 (45.5) | 10 (45.5) | |
Temperature (°C) | 37.3 ± 0.7 | 37.3 ± 0.9 | 0.93 |
Mean Arterial Pressure (mmHg) | 92 ± 13.6 | 93.6 ± 11.8 | 0.68 |
APACHEII score | 14 (12, 16) | 14 (11, 16) | 0.80 |
SOFA score | 8 (6, 9) | 8 (7, 9) | 0.25 |
The Fisher’s exact test was used for gender, the Pearson chi-square test for cause of TBI, type of TBI and surgical procedures, Mann-Whitney U test for GCS, APACHEII and SOFA scores, and independent samples t-test for the others. Values are presented as mean ± SD, median (IQR), or frequency (percent).