Table 3.
The clinical outcomes of study participants
| Variable | Taurine (n = 16) | Control (n = 16) | p-value* |
|---|---|---|---|
| APACHEII score | |||
| Day 1 | 14 (12, 17) | 13 (11, 15) | 0.34 |
| Day 14 | 12 (9, 13) | 13 (9, 14) | 0.31 |
| Changes (1, 14) | −4 (−6, −1) | −1 (− 4, 2) | 0.05 |
| p-value¥ | 0.003 | 0.32 | |
| SOFA score | |||
| Day 1 | 8 (6, 9) | 8 (6, 9) | 0.56 |
| Day 14 | 5 (4, 6) | 7 (5, 8) | 0.02 |
| Changes (1, 14) | −3 (−4, −1) | −1 (−3, 1) | 0.06 |
| p-value¥ | 0.003 | 0.06 | |
| GCS | |||
| Day 1 | 7 (7, 7) | 7 (7, 8) | 0.18 |
| Day 14 | 9 (7, 10) | 8 (6, 9) | 0.17 |
| Changes (1, 14) | 2 (0, 3) | 0.0 (−1, 1) | 0.03 |
| p-value¥ | 0.002 | 0.30 | |
| 30-day Mortality (N (%)) | 0.33 | ||
| Yes | 1 (6.3) | 4 (25) | |
| No | 15 (93.8) | 12 (75) | |
| Days on mechanical ventilation | 18 ± 9 | 23 ± 14 | 0.26 |
| Length of ICU stay | 22 (17, 31) | 21 (18, 39) | 0.96 |
Values are presented as mean ± SD, median (IQR) or Frequency (percent). Independent Samples T test was used for days on mechanical ventilation, Fisher’s exact test for 30-day mortality and Mann-Whitney U test for others. Within group comparison was made by by Wilcoxon for APACHEII and SOFA scores and GCS. *p-value for comparison between group; ¥ p-value for comparison within group.