Similarities and differences between mouse and human islets. The same endocrine cell types are present in both human and mouse islets but are spatially distinct and present in different ratios in each organism. All percentages are averages and represent a range of endocrine cell composition, especially in human alpha and beta cells, which can vary greatly from islet to islet. Red represent insulin (beta cells), green represents glucagon (alpha cells), orange is somatostatin (delta cells), and blue is pancreatic polypeptide (PP cells)