Table 1.
Exposure Conditions Inside Chambers Recorded During Experiments (Mean ± SD)
| Heated Tobacco Product, IQOS | Tobacco cigarette | ||
|---|---|---|---|
| Particulates PM2.5 (µg/m3) | Time-weighted average/day | 197 ± 47 | 269 ± 94 |
| Airborne nicotine (µg/m3) | Average/day | 432.5 ± 260.8* | 174.7 ± 106.2 |
| Serum cotinine (ng/mL) | Weeks 1 and 2 | 29.5 ± 19.7 | 35.6 ± 17.8 |
| Nicotine deposited on chamber walls (µg/cm2) | Average/day | 8.0 ± 2.2* | Below LOQ |
| Nicotine deposited on animal fur (µg/cm2) | Average/10 mice | Below LOQ | Below LOQ |
| Atmospheric pressure (mBar) | Average/day | 991.2 ± 9.1 | 993.5 ± 2.7 |
| Temperature (°C) | Average/day | 22.5 ± 0.2* | 21.7 ± 0.5 |
| Relative humidity (%) | Average/day | 70.5 ± 2.9 | 66.0 ± 7.1 |
All results are for n = 10 (10 samples collected every day), except for serum cotinine which are for n = 20 (10 mice serum samples per week). LOQ = limit of quantitation.
*A significant difference between IQOS and CS exposure conditions (p ≤ .05).