Table 5.
Treatment strategies, pattern and outcomes of Leishmanial keratitis
| Reference | n | Vision at first presentation | Leishmanial pattern | Corneal involvement | Treatment | Outcome |
|---|---|---|---|---|---|---|
| Chams[53] | 18 | NA | CL | Ulcerative keratitis | Systemic arsenic based compounds and topical methylene blue | 0.6-1.3 if treated during the first week 0.8-1.6 if treated during the between the second and fourth weeks 50% corneal perforations if treated after the fourth week |
| Van Os et al.[49] | 1 | OD: 0.3 OS: 0.2 | DCL | Superficial punctate keratitis and stromal infiltrate | Intracameral and intra-stromal amphotericin B, systemic antimonial and pentamidine | OD: 0.7 OS: 0.2 (note: the patient eventually underwent bilateral evisceration some time after publication of the article) |
| Roizenblatt[54] | 1 | Finger counting bilaterally | MCL | IK | Amphotericin B | Improvement |
| Cairns[61] | 1 | 1.1 bilaterally | CL | IK | 10% mepacrine infiltration topical steroids innefective | Full resolution |
| De Andrade[60] | NA | MCL | IK or ulcerative keratitis | Potassium tartrate or systemic antimonials | Variable | |
| Napier et al.[55] | 1 | OD: 1.3 OS: counting fingers | PKDL | Pannus and IK | Urea stibamine | OD: 0.8 OS: 1.5 |
n=Number of patients; NA=Not available; IK=Interstitial keratitis