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. 2021 Apr 30;69(5):1052–1060. doi: 10.4103/ijo.IJO_2232_20

Table 5.

Treatment strategies, pattern and outcomes of Leishmanial keratitis

Reference n Vision at first presentation Leishmanial pattern Corneal involvement Treatment Outcome
Chams[53] 18 NA CL Ulcerative keratitis Systemic arsenic based compounds and topical methylene blue 0.6-1.3 if treated during the first week 0.8-1.6 if treated during the between the second and fourth weeks 50% corneal perforations if treated after the fourth week
Van Os et al.[49] 1 OD: 0.3 OS: 0.2 DCL Superficial punctate keratitis and stromal infiltrate Intracameral and intra-stromal amphotericin B, systemic antimonial and pentamidine OD: 0.7 OS: 0.2 (note: the patient eventually underwent bilateral evisceration some time after publication of the article)
Roizenblatt[54] 1 Finger counting bilaterally MCL IK Amphotericin B Improvement
Cairns[61] 1 1.1 bilaterally CL IK 10% mepacrine infiltration topical steroids innefective Full resolution
De Andrade[60] NA MCL IK or ulcerative keratitis Potassium tartrate or systemic antimonials Variable
Napier et al.[55] 1 OD: 1.3 OS: counting fingers PKDL Pannus and IK Urea stibamine OD: 0.8 OS: 1.5

n=Number of patients; NA=Not available; IK=Interstitial keratitis