Table 1.
Recent and ongoing clinical trials involving electrical stimulation for gastrointestinal and related disorders. All trials registered with ClinicalTrials.gov with unique National Clinical Trial (NCT) number.
| Stimulation Site | Conditions | NCT | Intervention |
|---|---|---|---|
| Mouth | Gingival Recession | 2987231 | Vestibular Gingival Stimulation |
| Esophagus | Malnutrition | 2515123 | Esophageal Stimulation (E-Motion System) |
| GERD | 2749071 | Lower Esophageal Sphincter Stimulation (Endostim® System) | |
| Dysphagia | 3476265 | Lower Esophageal Sphincter Stimulation | |
| GERD | |||
| Stomach | Abdominal Pain | 4121325 | Gastric Electrical Stimulation (GES) (Enterra™ System) |
| Gastroparesis | 3123809 | Gastric Electrical Stimulation (GES) (Enterra™ System) | |
| Obesity | 3734081 | ODC System (Type 1 Capsule)|Device: ODC System (Type 2 Capsule) | |
| Abdomen | Neurogenic Bowel | 4307303 | Abdominal Functional Electrical Stimulation |
| GERD | 2500264 | Transcutaneous Electrical Nerve Stimulation (TENS) | |
| Dysmotility | 3316105 | Transcutaneous Electrical Nerve Stimulation (TENS) (Elira System) | |
| Obesity | |||
| Acustimulation | Gastroparesis | 4349891 | Transcutaneous Electroacupuncture |
| Postoperative Ileus | 3222557 | Transcutaneous Electroacupuncture | |
| Postoperative Intestinal Obstruction | 3086304 | Transcutaneous Electroacupuncture | |
| Scleroderma | 3294616 | Transcutaneous Electroacupuncture | |
| Gastroparesis | |||
| Vagus Nerve | Inflammatory Bowel Disease | 3953768 | Vagal Nerve Stimulation (VNS) |
| Inflammatory Bowel Disease | 3863704 | Transcutaneous Electrical Nerve Stimulation (TENS) | |
| Dyspepsia | 3603730 | Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) | |
| Gastroparesis | |||
| Irritable Bowel Syndrome | 2420158 | Transcutaneous Vagal Nerve Electrical Stimulation | |
| Gastroparesis | 3120325 | ||
| Functional Gastrointestinal Disorders | 3675321 | Active Auricular Neurostimulation | |
| Functional Gastrointestinal Disorders | 4247100 | Transcutaneous Electrical Nerve Stimulation (TENS) | |
| Brain | Functional Dyspepsia | 3869372 | Repetitive Transcranial Magnetic Stimulation (rTMS) |
| Irritable Bowel Syndrome | |||
| Obesity | 3943979 | Transcranial Direct-Current Stimulation (tDCS) | |
| Diabetes | |||
| Vestibular Nerve | Obesity | 3138382 | Vestibular Nerve Stimulator |
| Metabolic Syndrome |