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. 2021 Jun 8;16(6):e0252424. doi: 10.1371/journal.pone.0252424

Fig 3. Molecular mechanism of adenosine in regulation TGFβ signaling.

Fig 3

A) Representative Western blotting for pSMAD3 in mouse mammary fibroblast isolated from WT, A2a-KO, and A2b-KO mice. B) Scheme of adenosine signaling through A2a and A2b receptors. Targets for activation/inhibition of key components of signaling pathway are indicated. C) Representative Western blotting for Collagen (intracellular) and D) Quantitative analyzes of Western blotting using Image J software from 3 different experiments. *—p<0.05 compare to “TGFβ +NECA group”.