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. 2021 Jun 8;16(6):e0252955. doi: 10.1371/journal.pone.0252955

Table 2. Patient demographics and clinical data of the low and non-low BMI groups.

Variable Low BMI group (<18.5 kg/m2) (n = 103) Non-low BMI group (≥18.5 kg/m2) (n = 445) p-value
BMI (kg/m2), median (IQR) 16.8 (15.7–17.6) 22.9 (21.0–25.6) <0.001
Age (years), median (IQR) 79 (68–86) 73 (64–82) 0.003
Male, n (%) 63 (61.2) 282 (63.4) 0.73
Pre-existing conditions, n (%)
    Cardiovascular disease 12 (11.7) 61 (13.7) 0.63
    Stroke 17 (16.5) 60 (13.5) 0.43
    COPD 7 (6.8) 12 (2.7) 0.065
    Autoimmune disease 4 (3.9) 25 (5.6) 0.63
    Chronic liver disease 1 (1.0) 17 (3.8) 0.22
    Diabetes mellitus 21 (20.4) 143 (32.1) 0.023
    Chronic kidney disease 7 (6.8) 48 (10.8) 0.28
    Malignancy 13 (12.6) 44 (9.9) 0.47
Medications before admission, n (%)
    Steroids 10 (9.7) 59 (13.3) 0.41
    Immunosuppressant drugs 2 (1.9) 20 (4.5) 0.40
    Statins 10 (9.7) 69 (15.6) 0.161
    Anti-platelets 16 (15.5) 79 (17.8) 0.67
    β-blockers 14 (13.6) 48 (10.8) 0.49
Severity
    Lactate (mmol/L), median (IQR) 2.75 (2.08–4.03) 2.70 (1.90–4.40) 0.99
    Septic shock, n (%) 60 (58.8) 242 (55.1) 0.51
    APACHE II score, median (IQR) 20 (15–26) 19 (15–26) 0.57
    SOFA score, median (IQR) 7 (5–11) 8 (5–11) 0.34

Abbreviations: APACHE, Acute Physiology and Chronic Health Evaluation; BMI, body mass index; COPD, chronic obstructive pulmonary disease; IQR, interquartile range; SOFA, Sequential Organ Failure Assessment.