Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 25;12:687406. doi: 10.3389/fpls.2021.687406

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Colinas, Pollier, Vaneechoutte, Malat, Schweizer, De Milde, De Clercq, Guedes, Martínez-Cortés, Molina-Hidalgo, Sottomayor, Vandepoele and Goossens.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Swapping of DNA-binding domain (DBD) and activation domain (AD) of ORCA3 and 4. In order to get insight into the role of the AD in the synergistic up-regulation of MIA target genes, the respective DBDs and ADs of ORCA3 and 4 were swapped. (A) Cartoon showing the domain organization of ORCA3 and 4 and the respective chimeric proteins. (B) Combinatorial overexpression of CrMYC2a^D126N with ORCA3, 4 or chimeric proteins ORCA3-ORCA4 or ORCA4-ORCA3. These results suggest that the AD of ORCA3 improves the synergistic up-regulation of target genes. Cells labeled with different letters represent statistically significant differences (P < 0.05, ANOVA with Tukey’s correction for multiple comparisons).