TABLE 1.
The Demographics and Clinical Characteristics of Controls and Optic Disc Drusen Patients (Eyes)
| Controls (n= 53 eyes) | ODD (n= 29 eyes) | P value | |
|---|---|---|---|
| Age a (y) | 43.3 ± 2.0 | 37.9 ± 4.3 | .208 |
| Sex a, n (%) | .558 | ||
| Female | 19 (54.3) | 11 (64.7) | |
| Male | 16 (45.7) | 6 (35.3) | |
| LogMAR | 0.01 ± 0.01 | 0.02 ± 0.01 | .287 |
| VF MD (dB) | −0.36 ± 0.15 b | −5.07 ± 1.15 c | <.0001* |
| VF PSD (dB) | 1.44 ± 0.07 b | 4.26 ± 0.71 c | .001* |
| OCT Average RNFL (μm) | 93.1 ± 1.2 | 86.0 ± 4.9 | .006* |
| OCT Average GCC (μm) | 81.8 ± 0.8 | 77.7 ± 2.1 | .244 |
| OCTA Optic disc VAD | 0.45 ± 0.00 | 0.41 ± 0.01 | .011* |
| OCTA Macula VAD | 0.41 ± 0.00 | 0.41 ± 0.01 | .182 |
GCC = ganglion cell complex; LogMAR= Logarithm of the minimum angle of resolution; ODD = optic disc drusen; OCT = optical coherence tomography; OCTA = optical coherence tomography angiography; PSD = pattern standard deviation; RNFL = retinal nerve fiber layer; VAD = vessel area density; VF = visual field.
a
calculated from 35 controls and 17 ODD subjects
b
calculated from 17 eyes
c
calculated from 24 eyes.
Data are expressed as mean ± standard error except sex. Values were compared by Mann-Whitney test.
*
P < .05
Sex was compared by Chi-square test.