Table 3.
Univariable and Multivariable Analysis of Risk Factors for Thyroid Carcinoma
Characteristics | Univariable Analyses | Multivariable Analysis | ||||
---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | |
Age (years) | 0.964 | 0.947–0.980 | <0.001 | 0.959 | 0.939–0.979 | <0.001 |
Hashimoto’s thyroiditis | 2.212 | 1.173–4.169 | 0.014 | 2.437 | 1.162–5.111 | 0.018 |
TSH (<0.35 vs.0.35–4.94) | 0.293 | 0.086–1.003 | 0.051 | |||
(>4.94 vs 0.35–4.94) | 2.152 | 0.609–7.603 | 0.234 | |||
TPOAb (positive) | 2.096 | 1.102–3.986 | 0.024 | |||
TGAb (positive) | 2.255 | 1.190–4.275 | 0.013 | |||
Diameter of maximal nodules (cm) (US) | 0.603 | 0.466–0.780 | <0.001 | 0.706 | 0.541–0.919 | 0.010 |
Composition of maximal nodules (mixed cystic and solid vs cystic) | 0.864 | 0.267–2.797 | 0.808 | |||
(solid vs cystic) | 3.000 | 0.975–9.235 | 0.055 | |||
Punctate echogenic foci | 3.202 | 1.980–5.176 | <0.001 | 2.837 | 1.598–5.286 | <0.001 |
Abbreviations: TPOAb, thyroid peroxidase antibodies; TGAb, thyroglobulin antibodies; TSH, thyroid-stimulating hormone; US, ultrasonography.