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. 2021 Jun 4;16:1661–1675. doi: 10.2147/COPD.S314640

Figure 4.

Figure 4

Overexpression of HDAC2 inhibits CSE-induced atrophy in C2C12 cells. (A) Effects of LV-HDAC2 Overexpression on HDAC2 Protein and mRNA. (B) Immunofluorescence measurement of the mean myotube diameter after 24 hours of 0.3% CSE between the different groups; 100×. (C) The protein expression level of MURF1, MAFbx, HDAC2 in cells with or without 0.3% CSE. (D) The mRNA level of MURF1, MAFbx in cells with or without 0.3% CSE. Values are expressed as means±SD. Experiments were repeated 3 times with similar results. *p<0.05 vs control NC group (LV-NC), #p<0.05 vs CSE+LV-NC group.