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. 2021 Jun 4;16:1661–1675. doi: 10.2147/COPD.S314640

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© 2021 Li et al.

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Overexpression of HDAC2 Inhibits Senescence in C2C12 Cells. (A) β-Galactosidase staining measurement of cellular senescence after 24 hours of 0.3% CSE between the different groups, 100×. (B) The protein expression level of P53, P21, SMP30 in cells with or without 0.3% CSE. (C) The mRNA level of P53, P21 in cells with or without 0.3% CSE. (D) The protein expression level of NF-κBp65 and IKK in cells with or without 0.3% CSE. Values are expressed as means±SD. Experiments were repeated 3 times with similar results. *p<0.05 vs control NC group (LV-NC), ^#p<0.05 vs CSE+LV-NC group.