Table 2.
Clinical characteristics of donors where recurrent type 1 diabetes developed after SPK transplantation
| Characteristic | Donor no. | ||
|---|---|---|---|
| nPOD 3626 | nPOD 3678 | nPOD 3681 | |
| Sex | M | M | M |
| Age at type 1 diabetes onset, years | 29 | 14 | 12 |
| Age at transplant, years | 43 | 39 | 35 |
| Ab status at transplant | |||
| GADA | − | + | − |
| IA-2A | + | − | − |
| ZnT8A | − | − | − |
| Age at biopsy, years | 63 | 49 | 40 |
| Ab status at biopsy | |||
| GADA | + | + | − |
| IA-2A | + | + | + |
| ZnT8A | − | + | + |
| HbA1c at biopsy, mmol/mol (%) | 115.3 (12.7) | 94.5 (10.6) | 93.4 (10.7) |
| Age at biopsy, years | 63 | 49 | 40 |
| Time from transplant to diabetes recurrence, years | 17.2 | 8 | 4.9 |
| Duration of diabetes recurrence at biopsy, years | 1.4 | 1.4 | 0.6 |
Ab, antibody; M, male sex