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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Biochem Pharmacol. 2021 Feb 3;189:114453. doi: 10.1016/j.bcp.2021.114453

Figure 3.

Figure 3.

(A) Zeta potential changes of IL-12 PMet-P(cdmPEG2K) micelleplexes and IL-12/DOX PMet-P(cdmPEG2K) micelleplexes incubated at pH 7.4 and pH 6.8 in Hepes buffer. (B) Particle size changes in IL-12/PEI25K polyplexes, blank and DOX-loaded PMet-P(cdmPEG2K) micelles, IL-12 and IL-12/DOX PMet-P(cdmPEG2K) micelleplexes as a function of incubation time with 1 mg/mL BSA solution at pH 7.4. (C) Cumulative DOX release profiles of DOX-loaded and IL-12/DOX co-loaded PMet-P(cdmPEG2K) micelleplexes into the medium at pH 7.4 and pH 6.8 with DOX as the control.