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IC50 values of DOX solution, DOX-loaded micelles and IL-12/DOX co-loaded PMet-P(cdmPEG2K) micelleplexes against 4T1.2 cells after 72 h of incubation in culture medium at pH 7.4 and pH 6.8.
| Micellar formulations | IC50 at pH 7.4 (μg/mL) | IC50 at pH 6.8 (μg/mL) |
|---|---|---|
| DOX solution | 0.381 | 0.443 |
| DOX micelles | 0.998 | 0.768 |
| IL-12/DOX micelleplexes | 0.819 | 0.348 |
