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Maternal allergic inflammation increases the number of mast cells in the perinatal hippocampus. (A) OVA and vehicle offspring have similar numbers of mast cells throughout the brain two hours post-challenge on GD15. N’s = 7/group. (B – D) Males had more total, granulated, and degranulated mast cells in and near the hippocampus compared to females. (B and C) Allergic challenge increased total and granulated mast cell numbers. N = 3/group/sex. HPC = hippocampus, MC = mast cells.
