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Synergism studies using BCL inhibitors and PROTAC 2. (A) Structure of Bcl2 inhibitors Navitoclax (ABT-263); Venetoclax (ABT-199); WEHI-539; (B) Growth inhibitory effects of different inhibitors combinations at 5 μM, (C) Combination index (Cl) values for the three Bcl2 inhibitors and PROTAC 2 combinations.
