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. 2021 Jun 8;11:12053. doi: 10.1038/s41598-021-90938-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differential expression along the cork growing season. (a) Venn diagrams showing DEGs, upregulated (UP) and downregulated (DOWN), between June/April, July/April and June/July. The yellow circle includes the genes identified in both June/April and July/April comparisons. (b) Hierarchical clustering of cork samples based on the expression of DEG along the growing season. C. K-means clusters of co-expressed genes in April, June and July. Cluster 1 and 3 contain genes downregulated in April and upregulated in June and July, whereas cluster 2 and 4 showed the opposite pattern containing genes upregulated in April and downregulated in June and July.