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. 2021 Jun 8;11:12094. doi: 10.1038/s41598-021-91753-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Linear regression, comparing metabolic measures with BMI categorized according to cancer preventive recommendations (BMI < 25 kg/m² or ≥ 25 kg/m² (referent). Models adjusted for age, sex and study (pilot or larger sample). Significance determined at p < 0.05 and q < 0.10. Bar heights represent the magnitude of the beta-coefficient from linear regression. Red bars indicate positive betas and blue bars indicate negative betas. Full names of metabolic measures listed are provided in the Supplemental Tables. Figure generated with R version 4.0.3⁴⁴.