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. 2021 Jun 8;11:12080. doi: 10.1038/s41598-021-91570-z

Table 3.

Crude and adjusted odd ratios (95% confidence interval) of hyperuricemia for osteoporosis according their past medical histories.

Characteristics Odd ratios for osteoporosis
Crude P value Adjusted P value
With hypertension (n = 37,477)
Hyperuricemia 0.59 (0.53–0.67)  < 0.001* 0.83 (0.73–0.94) 0.005*
Control 1.00 1.00
Without hypertension (n = 130,884)
Hyperuricemia 0.45 (0.39–0.51)  < 0.001* 0.75 (0.64–0.87)  < 0.001*
Control 1.00 1.00
With diabetes mellitus (n = 13,289)
Hyperuricemia 0.83 (0.66–1.04) 0.106 0.88 (0.69–1.13) 0.315
Control 1.00 1.00
Without diabetes mellitus (n = 155,072)
Hyperuricemia 0.55 (0.50–0.61)  < 0.001* 0.77 (0.69–0.86)  < 0.001*
Control 1.00 1.00
With hyperlipidemia (n = 22,193)
Hyperuricemia 0.48 (0.41–0.57)  < 0.001* 0.74 (0.61–0.89) 0.002*
Control 1.00 1.00
Without hyperlipidemia (n = 146,168)
Hyperuricemia 0.59 (0.53–0.66)  < 0.001* 0.81 (0.72–0.91)  < 0.001*
Control 1.00 1.00

*Logistic regression model, Significance at P < 0.05.

Models adjusted for age, sex, income group, BMI, smoking, alcohol consumption, hypertension, diabetes mellitus, hyperlipidemia histories and nutritional intake (total calories, protein, fat, carbohydrate intake, calcium, and phosphorous intake).