Figure 5.

Results of fitting the agent-based model (ABM) to the experimental data from C. albicans and S. aureus infection using the method of adaptive regular grid search. The parameter space is shown for fitting the ABM to experimental data, where blood samples from healthy donors and HLM patients before surgery (pre-operative), immediately after surgery (post-operative) and one day after admission to intensive care (post-operative + 1d) were infected with either C. albicans (left column) or S. aureus (right column). Colors of the points refer to the weighted least squares error $E\left(\overrightarrow{p}\right)$ for each parameter set $\overrightarrow{p}=\left(D_N,,,D_M\right)$. The optimal parameter set is marked with a white dot. All parameter sets with a mean LSE that lies within the SD of the optimal parameter set are marked with a black dot.