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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Clin Pharmacol Ther. 2021 Jan 1;110(4):975–985. doi: 10.1002/cpt.2135

Figure 4.

Figure 4

Principal component analyses showing fine AFR population substructure. Principal components were computed from merging the 1KG AFR subpopulations and the training set (PNAT2+KIS3 AFR) samples. A) 1KG AFR subpopulations and training set (PNAT2+KIS3 AFR) participants plotted. B) 1KG AFR subpopulations plotted only. C) PNAT2 participants split by geographic recruitment sites plotted only. D) KIS3 participants plotted only.

(ACB: 1KG African Caribbeans; ASW: 1KG Southwest Americans; LWK: 1KG Luhya; ESN: 1KG Esan; GWD: 1KG Gambian; MSL: 1KG Mende; YRI: 1KG Yoruba).

Note: The PNAT2 Toronto site was excluded from the analyses in this Figure to the small sample size (N=14)