Table 1.

Basic characteristics of participants with different genotypes of rs189037.

Characteristics	Young	Middle-aged and elderly	Centenarians	Pa	Pb	Pc	Pd
	(n = 250)	(n = 250)	(n = 547)
Age (year)e	32 (28, 37)	64 (55, 73)	102 (101, 104)	<0.001	<0.001	<0.001	<0.001
Males (%)	137 (54.8)	156 (62.4)	93 (17.0)	<0.001	0.085	<0.001	<0.001
Han nationality (%)	198 (79.2)	185 (74.0)	471 (86.1)	<0.001	0.170	0.014	<0.001
Hypertension (%)	3 (1.2)	124 (49.6)	462 (84.5)	<0.001	<0.001	<0.001	<0.001
Systolic blood pressure (mmHg)e	109 (102, 116)	123 (113, 136)	151 (135, 171)	<0.001	<0.001	<0.001	<0.001
Diastolic blood pressure (mmHg)e	71 (66, 77)	69 (62, 76)	75 (66, 83)	<0.001	0.009	<0.001	<0.001
Fasting blood glucose (mmol/L)e	4.68 (4.44, 4.92)	5.93 (5.16, 8.07)	4.82 (4.20, 5.74)	<0.001	<0.001	0.015	<0.001
Triglyceride (mmol/L)e	1.03 (0.75, 1.57)	1.37 (1.03, 1.94)	1.03 (0.80, 1.43)	<0.001	<0.001	0.946	<0.001
Total cholesterol (mmol/L)e	4.70 (4.05, 5.28)	4.07 (3.25, 4.87)	4.57 (4.06, 5.18)	<0.001	<0.001	0.482	<0.001
Low-density lipoprotein cholesterol (mmol/L)e	2.76 (2.29, 3.23)	2.41 (1.81, 3.16)	2.71 (2.29, 3.24)	<0.001	<0.001	0.601	<0.001
High-density lipoprotein cholesterol (mmol/L)e	1.40 (1.17, 1.87)	1.08 (0.85, 1.41)	1.40 (1.18, 1.67)	<0.001	<0.001	0.082	<0.001
C (%)	312 (62.4)	268 (53.6)	655 (59.9)	0.013	0.005	0.019	0.338
CC [n (%)]	91 (36.4)	67 (26.8)	195 (35.6)	0.029	0.012	0.041	0.266
CT [n (%)]	130 (52.0)	134 (53.6)	265 (48.4)
TT [n (%)]	29 (11.6)	49 (19.6)	87 (15.9)
Hardy–Weinberg equilibrium	0.232	0.471	0.982

^aCentenarians/middle-aged and elderly/young.

^bMiddle-aged and elderly/young.

^cCentenarians/young.

^dCentenarians/middle-aged and elderly.

^eMedian (interquartile range).