Table 4.
Associations of cardiac structure and function with different genotypes of rs189037 in the centenarians.
| Characteristics | TT/CT | TT/CC | TT/CT+CC | CT/CC | CT/TT+CC | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Multivariate logistic regressiona | Exp(B) (95% CI) | P | Exp(B) (95% CI) | P | Exp(B) (95% CI) | P | Exp(B) (95% CI) | P | Exp(B) (95% CI) | P |
| Interventricular septum thickness (mm) |
1.181 (1.001–1.394) |
0.049 | 1.158 (0.987–1.358) |
0.071 | 1.154 (0.999–1.333) |
0.051 | 1.002 (0.888–1.131) |
0.971 | 0.953 (0.854–1.064) |
0.394 |
| Left ventricular posterior wall thickness (mm) |
1.152 (1.002–1.324) |
0.047 | 1.244 (1.021–1.517) |
0.030 | 1.140 (1.009–1.288) |
0.036 | 0.978 (0.879–1.089) |
0.686 | 0.929 (0.832–1.037) |
0.190 |
| Left ventricular end-diastolic diameter (mm) |
1.055 (0.999–1.113) |
0.055 | 1.007 (0.952–1.064) |
0.818 | 1.031 (0.980–1.084) |
0.235 | 0.947 (0.908–0.988) |
0.011 | 0.948 (0.914–0.985) |
0.006 |
| Right ventricle end-diastolic diameter (mm) |
0.988 (0.923–1.057) |
0.716 | 1.059 (0.984–1.141) |
0.127 | 1.015 (0.954–1.080) |
0.644 | 1.064 (1.009–1.123) |
0.022 | 1.047 (0.999–1.097) |
0.057 |
| Left atrium end-systolic diameter (mm) |
0.994 (0.946–1.045) |
0.822 | 1.002 (0.951–1.054) |
0.951 | 0.997 (0.951–1.045) |
0.895 | 1.016 (0.976–1.058) |
0.434 | 1.013 (0.978–1.049) |
0.464 |
| Right atrium end-systolic diameter (mm) |
1.048 (0.984–1.116) |
0.143 | 1.060 (0.994–1.130) |
0.074 | 1.053 (0.995–1.115) |
0.074 | 1.009 (0.961–1.060) |
0.707 | 0.991 (0.949–1.035) |
0.687 |
| Pulmonary artery diameter (mm) |
0.939 (0.837–1.053) |
0.280 | 0.926 (0.830–1.033) |
0.168 | 0.932 (0.841–1.033) |
0.177 | 0.977 (0.907–1.052) |
0.532 | 0.999 (0.933–1.070) |
0.978 |
| Aorta diameter (mm) |
0.999 (0.936–1.065) |
0.964 | 0.970 (0.907–1.038) |
0.379 | 0.985 (0.929–1.046) |
0.630 | 0.972 (0.927–1.019) |
0.238 | 0.980 (0.939–1.024) |
0.370 |
| Left ventricular ejection fraction (%) |
1.035 (0.960–1.116) |
0.368 | 0.985 (0.913–1.064) |
0.705 | 1.011 (0.945–1.082) |
0.746 | 0.955 (0.905–1.008) |
0.095 | 0.958 (0.911–1.007) |
0.094 |
a
With adjustment of age, sex, nationality, hypertension, fasting blood glucose, total cholesterol, triglyceride, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol.