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. 2021 May 26;8:658908. doi: 10.3389/fcvm.2021.658908

Table 5.

Basic characteristics of middle-aged and elderly with different genotypes of rs189037.

Characteristics TT CT CC Pa Pb Pc Pd
(n = 87) (n = 265) (n = 195)
Age (year)e 65 (58, 73) 64 (56, 73) 63 (53, 73) 0.888 0.758 0.544 0.905
Males (%) 30 (34.5) 82 (30.9) 44 (22.6) 0.059 0.539 0.036 0.046
Han nationality (%) 37 (42.5) 101 (38.1) 47 (24.1) 0.001 0.464 0.001 0.002
Hypertension (%) 24 (27.6) 66 (24.9) 34 (17.4) 0.082 0.619 0.051 0.055
Systolic blood pressure (mmHg)e 129 (117, 139) 122 (109, 131) 128 (114, 142) 0.054 0.053 0.997 0.051
Diastolic blood pressure (mmHg)e 67 (60, 76) 68 (62, 76) 70 (61, 79) 0.617 0.369 0.409 0.794
Fasting blood glucose (mmol/L)e 5.88 (5.24, 8.29) 5.80 (5.04, 7.99) 6.33 (5.26, 8.23) 0.572 0.474 0.811 0.345
Triglyceride (mmol/L)e 1.29 (1.04, 1.66) 1.33 (0.94, 1.94) 1.58 (1.14, 2.08) 0.172 0.644 0.058 0.143
Total cholesterol (mmol/L)e 3.61 (3.02, 4.44) 4.00 (3.25, 4.89) 4.43 (3.45, 5.17) 0.044 0.125 0.015 0.141
Low-density lipoprotein cholesterol (mmol/L)e 2.21 (1.65, 2.77) 2.41 (1.80, 3.11) 2.74 (1.98, 3.37) 0.037 0.251 0.013 0.066
High-density lipoprotein cholesterol (mmol/L)e 0.99 (0.81, 1.34) 1.10 (0.86, 1.44) 1.10 (0.86, 1.48) 0.397 0.247 0.186 0.796
Interventricular septum thickness (mm)e 10 (9, 13) 10 (9, 11) 10 (9, 10) 0.120 0.090 0.062 0.435
Left ventricular posterior wall thickness (mm)e 10 (9, 12) 10 (9, 10) 10 (9, 10) 0.067 0.037 0.043 0.637
Left ventricular end-diastolic diameter (mm)e 48 (44, 56) 45 (43, 48) 47 (44, 51) 0.034 0.015 0.485 0.100
Right ventricle end-diastolic diameter (mm)e 30 (28, 34) 31 (28, 34) 32 (30, 34) 0.537 0.515 0.264 0.511
Left atrium end-systolic diameter (mm)e 33 (31, 35) 33 (31, 36) 33 (31, 36) 0.854 0.628 0.599 0.906
Right atrium end-systolic diameter (mm)e 32 (30, 34) 32 (30, 35) 33 (31, 36) 0.553 0.601 0.283 0.456
Pulmonary artery diameter (mm)e 21 (20, 23) 22 (20, 23) 21 (20, 23) 0.425 0.654 0.468 0.198
Aorta diameter (mm)e 30 (29, 32) 32 (29, 34) 32 (29, 34) 0.291 0.116 0.373 0.568
Left ventricular ejection fraction (%)e 60 (56, 60) 60 (60, 65) 60 (55, 63) 0.070 0.032 0.697 0.125
a

TT/CT/CC.

b

TT/CT.

c

TT/CC.

d

CT/CC.

e

Median (interquartile range).