Table 2.
Regression analysis for the TA Hsp-70 and 8-OHdG levels in patients with bronchopulmonary dysplasia.
| Univariate analysis (crude) | Multiple analysis (adjusted) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Odds ratio | 95% C.I. | P-value | Odds ratio | 95% C.I. | P-value | |||||
| GA | 0.702 | 0.573 | – | 0.860 | 0.001 | 0.707 | 0.507 | – | 0.986 | 0.041 |
| BW | 0.995 | 0.992 | – | 0.997 | <0.001 | |||||
| Apgar score (1-min) | 0.752 | 0.595 | – | 0.949 | 0.017 | |||||
| Apgar score (5-min) | 0.663 | 0.493 | – | 0.892 | 0.007 | |||||
| Surfactant use (Yes vs. No) | 7.778 | 2.736 | – | 22.109 | <0.001 | 54.607 | 1.609 | – | 1853.712 | 0.026 |
| Ventilator days | 1.050 | 1.027 | – | 1.074 | <0.001 | |||||
| O2 days | 1.071 | 1.044 | – | 1.100 | <0.001 | |||||
| RDS (Yes vs. No) | 4.685 | 1.734 | – | 12.657 | 0.002 | |||||
| ROP (Yes vs. No) | 5.088 | 2.103 | – | 12.309 | <0.001 | |||||
| TA 8-OHdG-day 1 | 1.062 | 1.017 | – | 1.108 | 0.006 | |||||
| TA Hsp-70-day 1 | 1.010 | 1.002 | – | 1.018 | 0.011 | |||||
| TA 8-OHdG-day 28 | 1.093 | 1.050 | – | 1.137 | <0.001 | 1.099 | 1.025 | – | 1.179 | 0.008 |
| TA Hsp-70-day 28 | 1.012 | 1.006 | – | 1.018 | <0.001 | 1.011 | 1.003 | – | 1.019 | 0.005 |
| Δ TA 8-OHdG | 1.068 | 1.033 | – | 1.104 | <0.001 | |||||
| Δ TA Hsp-70 | 1.011 | 1.006 | – | 1.016 | <0.001 | |||||
Δ = day 28–day 1.
BW, birth weight; GA, gestational age; RDS, respiratory distress syndrome; TA, tracheal aspirates.