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. 2021 May 26;8:670188. doi: 10.3389/fmed.2021.670188

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Copyright © 2021 Niu, Huang, Qiao, Liu, Chen and Zhong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression and distribution of Beclin1, LC3, and LAMP2 in AB and NOM tissues by immunohistochemistry. (A) Beclin1 is positively expressed in the nucleus of epithelial cells in NOM tissues and is positively expressed in the cytoplasm of epithelial cells in AB tissues. (B) Quantitative analysis results showing a lower expression level of Beclin1 in AB tissues than in NOM tissues. (C) LC3 is negatively expressed in NOM and is positively expressed in the nuclei of epithelial cells in AB tissues. (D) Quantitative analysis showing a higher expression level of LC3 in AB tissues than in NOM tissues. (E) LAMP2 is negatively expressed in NOM and is positively expressed in the cytoplasm and cell membrane of epithelial cells in AB tissues. (F) Quantitative analysis for a higher expression level of LAMP2 in AB tissues than in NOM tissues. Bar: 100 μm. Magnification: 200 ×. *P < 0.05; **P < 0.01.