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. 2021 Jun 8;12:3452. doi: 10.1038/s41467-021-23687-8

Fig. 1. Flowchart illustrating the relationship between baseline clinical diagnoses and underlying pathology in all 32 progressive apraxia of speech patients.

Fig. 1

Thirty-two patients with progressive apraxia of speech were included in the study. Fifteen of these patients were diagnosed with primary progressive apraxia of speech (PPAOS), of which nine had corticobasal degeneration (CBD) pathology and six had progressive supranuclear palsy (PSP) pathology. Twelve of the 32 patients were diagnosed with both apraxia of speech and agrammatism (AOS-PAA), of which 8 had CBD and 4 had PSP pathology. The last five patients were diagnosed with apraxia of speech that was embedded in other symptoms and signs (+AOS). These five patients had frontotemporal lobar degeneration pathology with TAR DNA binding of 43Kda (FTLD-TDP) (either type A or B) and Pick disease (PiD) pathologies, with one patient also having argyrophilic grains disease (AGD). The number of patients with the phonetic and prosodic subtype of apraxia of speech is shown in each box.