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. 2021 Jun 8;11:12040. doi: 10.1038/s41598-021-90545-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of P. harmala on AlCl₃-induced neuronal loss in hippocampal CA1 and DG regions. (a) Representative images of Nissl staining across hippocampal CA1 and DG sections (scale bar 50 μm). The lower panel shows the effect of P. harmala treatment on the number of surviving neurons in hippocampal (b) CA1 and (c) DG regions. Values represent mean ± SD (n = 3). Statistical analysis was carried out by one-way ANOVA followed by Tukey’s Multiple Comparisons test. (*) Significantly different from CONT and (@) AlCl₃ groups at p < 0.05; AlCl₃ aluminum chloride, CONT control, CA1 cornu Ammonis 1, DG dentate gyrus, Ph Peganum harmala.