Fig. 7. FcγRIIb and LilrB2 affect the kinetics of Aβ polymerization in a manner similar to PrP.

ThT curves for polymerization of unlabeled Aβ (5 μM) in the presence of increasing concentrations of recombinant PrP (a), FcγRIIb (b), LilrB2 (c) and calmodulin (d). e Effect of receptors on the half-times for Aβ polymerization, derived from the data in (a–d). Data represent mean ± S.E. Half-time values that are significantly different from control are indicated: *P < 0.05, **P < 0.01, and ***P < 0.001 (two-sided Student’s t-test). Each curve shown in a–d is the average of 3 replicates, and each condition repeated at least 5 times.