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. 2021 May 26;11:663263. doi: 10.3389/fonc.2021.663263

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Copyright © 2021 Yu, Mao, Sun, Hu, Wang, Xu, Liu, Chen, Xu and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of the prognostic signature for KIRC patients in testing set and overall set. Kaplan-Meier curves showed that the high-risk group had worse overall survival (OS) than the low-risk group in the testing set (A) and overall set (B). Receiver operating characteristic (ROC) curves for the prognostic signature and its AUC value in the testing set (C) and overall set (D). ROC curves and their AUC value represented 1-, 3-, and 5-year predictions in the testing set (E) and overall set (F). Scatter dot plot showed the outcomes between the survival status and risk score of KIRC patients in high- and low-group; Risk score distribution plot showed the distribution of high-risk and low-risk KIRC patients; Heatmap of the five m6A-related lncRNA expression profiles showed the expression of risk lncRNAs in high-risk and low-risk group in the testing set (G) and overall set (H), separately.