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. 2021 May 26;11:665192. doi: 10.3389/fonc.2021.665192

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Copyright © 2021 Li, Qin, Zhao, Cao, Yang, Wang, Li, Zhou and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Significantly enriched GO annotations of METTL18 related genes in HCC. (A) Top seven of biological process enrichment related to METTL18 related genes with bar graph. (B–E) Enrichment plots from the gene set enrichment analysis (GSEA). Several pathways and biological processes were differentially enriched in METTL18-related HCC, including G2M checkpoint, KRAS signaling, mitotic spindle and E2F targets. NES, normalized enrichment score; p. adj, adjusted P value; FDR, false discovery rate.