Table 2.
METTL18 expression association with clinical pathological characteristics (logistic regression).
| Characteristics | the number of patients involved | Odds Ratio (OR) | P value |
|---|---|---|---|
| T stage (T2&T3&T4 vs. T1) | 368 | 1.06(1.02-1.10) | 0.002 |
| N stage (N1 vs. N0) | 256 | 0.89(0.68-1.07) | 0.326 |
| M stage (M1 vs. M0) | 270 | 1.06(0.93-1.16) | 0.283 |
| Pathologic stage (Stage II& Stage III& Stage IV vs. Stage I) | 347 | 1.05(1.02-1.09) | 0.005 |
| Histologic grade (G3&G4 vs. G1&G2) | 366 | 1.08(1.04-1.12) | <0.001 |
| Residual tumor (R1&R2 vs. R0) | 342 | 1.03(0.96-1.08) | 0.358 |
| Child-Pugh grade (B&C vs. A) | 239 | 0.98(0.90-1.05) | 0.654 |
| Adjacent hepatic tissue inflammation (Mild& Severe vs. None) | 234 | 1.06(1.02-1.11) | 0.010 |
| Vascular invasion (Yes vs. No) | 315 | 1.05(1.02-1.10) | 0.007 |
| Tumor status (With tumor vs. Tumor free) | 352 | 1.03(1.00-1.07) | 0.053 |
| TP53 status (Mut vs. WT) | 358 | 1.03(1.00-1.07) | 0.062 |
| Gender (Male vs. Female) | 371 | 1.00(0.96-1.03) | 0.786 |
| Race (Asian& Black or African American vs. White) | 359 | 1.07(1.04-1.12) | <0.001 |
| Age (>60 vs. <=60) | 370 | 0.98(0.95-1.01) | 0.191 |
| AFP (ng/ml) (>400 vs. <=400) | 278 | 1.04(1.00-1.08) | 0.027 |