Table 2.
Cycle characteristics and ART outcomes.
Variable | Day-3 Serum AMH (ng/ml) | P value | ||||
---|---|---|---|---|---|---|
Group 1, ≤6.77 N=611 | Group 2,6.77-14.30 n=1216 | Group 3, ≥14.30 N=609 | p-value Low vs. High | p-value Low vs. Average | p-value Average vs. High | |
Intracytoplasmic sperm injection, % | 29.5 (180/611) | 31.2 (379/1216) | 28.7 (175/609) | NS | NS | NS |
Ovarian stimulation protocols | 0.044 | NS | NS | |||
GnRH Antagonist, % | 11.8 (72/611) | 13.2 (160/1216) | 16.6 (101/609) | |||
GnRH agonist, % | 88.2 (539/611) | 86.8 (1056/1216) | 83.4 (508/609) | |||
Gonadotropin dose, IU | 2116 ± 782 | 1863 ± 783 | 1740 ± 785 | <0.001 | <0.001 | <0.001 |
E2 on hCG, pg/mL | 2810 ± 1670 | 3561 ± 2105 | 4349 ± 2841 | <0.001 | <0.001 | <0.001 |
P on hCG day, ng/mL | 0.84 ± 0.48 | 0.86 ± 0.57 | 0.90 ± 0.65 | NS | NS | NS |
No. of oocytes retrieved | 13.97 ± 5.81 | 16.00 ± 6.52 | 16.84 ± 8.04 | <0.001 | <0.001 | NS |
No. of MII oocytes | 12.21 ± 5.32 | 14.01 ± 5.95 | 14.83 ± 7.58 | <0.001 | <0.001 | NS |
Oocyte maturation rate | 0.8786 ± 0.1333 | 0.8795 ± 0.1325 | 0.8801 ± 0.1325 | NS | NS | NS |
Endometrial thickness, mm | 11.96 ± 2.64 | 11.95 ± 2.63 | 11.78 ± 2.40 | NS | NS | NS |
No. of >14 mm follicles | 12.91 ± 4.58 | 14.84 ± 4.90 | 16.68 ± 6.12 | <0.001 | <0.001 | <0.001 |
Available embryo rate | 0.6552 ± 0.1930 | 0.6466 ± 0.1993 | 0.6418 ± 0.2197 | NS | NS | NS |
No. of embryos transferred in fresh ET | 1.20 ± 0.67 | 1.08 ± 0.70 | 0.90 ± 0.73 | <0.001 | <0.001 | 0.001 |
Live birth rate, % | 46.6 (285/611) | 40.5 (492/1216) | 39.4 (240/609) | 0.031 | 0.034 | NS |
Cumulative live birth rate, % | 68.7 (272/396) | 70.4 (643/914) | 71.3 (342/480) | NS | NS | NS |
Clinical pregnancy rate, % | 53.0 (324/611) | 47.0 (571/1216) | 45.5 (277/609) | 0.025 | 0.043 | NS |
Normal fertilization rate, % | 61.7 (5266/8534) | 59.9 (11664/19462) | 59.9 (6144/10254) | 0.038 | 0.016 | NS |
NS, not statistically significant.