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. 2021 May 26;12:667782. doi: 10.3389/fmicb.2021.667782

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Copyright © 2021 Huang, Wong, Wang, Hashimoto, Lin, Lee, Wu, Wang, Lin, Jeng, Wang, Chen and Teng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Linear comparison of pEC41 with other IncM group plasmids. Black arrows indicate the common regions shared among the plasmids. The tra locus contains tra genes involved in conjugal transfer. The partition system (parAB) and postsegregational killing system (pemIK) are indicated by purple arrows. Resistance genes are indicated by blue arrows. Insertion sequences and transposon components are indicated by yellow arrows. The fec system on pEC41 is indicated with green arrows. The replicase gene repA is indicated by red arrows. The direction of arrows indicates the direction of the ORF. Gray shading denotes regions of shared homology among different plasmids. Diagrams were drawn from sequences available under the following GenBank accession numbers: pEC41 (MW548582), pCTX-M-3 (AF550415), pLM6771 (KX009507), pCTXM360 (EU938349), pEl1573 (JX101693), pNDM-OM (JX988621), and pEL60 (AY422214). The comparison map was generated using Easyfig software (Sullivan et al., 2011).