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. 2021 Jun;10(3):301–307. doi: 10.21037/hbsn.2019.11.09

Table 1. Patient demographics.

Clinicopathological parameters No metastasis, N=135 Confirmed metastasis, N=17 P
Age (years) 63 [19–84] 55 [22–82] 0.050
Male: female 107:28 15:2 0.580
Hepatitis B 97 [72] 16 [94] 0.140
Hepatitis C 7 [5] 0 [0] 0.516
Comorbidity 70 [52] 7 [41] 0.407
Child-Pugh class 0.005*
   A 114 [84] 9 [53]
   B 17 [13] 7 [41]
   C 3 [2] 0 [0]
ICG (%) 10.5 (4.9–46.5) 12.8 (5.0–21.9) 0.813
Bilirubin (μmol/L) 11 [4–100] 14 [5–39] 0.273
Albumin (g/L) 39 [23–51] 35 [26–42] 0.203
Platelet (×109/L) 178 [36–693] 222.5 [63–524] 0.013*
Creatinine (μmol/L) 84 [40–283] 74 [53–141] 0.923
Size of largest tumor (cm) 5 (1.0–22.1) 11.8 (2.3–20.0) 0.003*
Disease pattern 0.008*
   Solitary 78 [58] 4 [24]
   Multifocal 57 [42] 13 [76]
Bilobar involvement 41 [30] 12 [71] 0.001*
AFP 0.002*
   <400 ng/mL 101 [75] 6 [35]
   ≥400 ng/mL 33 [24] 11 [65]
Invasion of major branch of portal or hepatic vein 21 [16] 5 [29] 0.277

Data in median [range] or number of patients [percent] or otherwise stated. *, statistically significant. ICG, indocyanine green retention rate at 15 minutes after injection; AFP, alpha-fetoprotein.