Table 1. Patient demographics.
Clinicopathological parameters | No metastasis, N=135 | Confirmed metastasis, N=17 | P |
---|---|---|---|
Age (years) | 63 [19–84] | 55 [22–82] | 0.050 |
Male: female | 107:28 | 15:2 | 0.580 |
Hepatitis B | 97 [72] | 16 [94] | 0.140 |
Hepatitis C | 7 [5] | 0 [0] | 0.516 |
Comorbidity | 70 [52] | 7 [41] | 0.407 |
Child-Pugh class | 0.005* | ||
A | 114 [84] | 9 [53] | |
B | 17 [13] | 7 [41] | |
C | 3 [2] | 0 [0] | |
ICG (%) | 10.5 (4.9–46.5) | 12.8 (5.0–21.9) | 0.813 |
Bilirubin (μmol/L) | 11 [4–100] | 14 [5–39] | 0.273 |
Albumin (g/L) | 39 [23–51] | 35 [26–42] | 0.203 |
Platelet (×109/L) | 178 [36–693] | 222.5 [63–524] | 0.013* |
Creatinine (μmol/L) | 84 [40–283] | 74 [53–141] | 0.923 |
Size of largest tumor (cm) | 5 (1.0–22.1) | 11.8 (2.3–20.0) | 0.003* |
Disease pattern | 0.008* | ||
Solitary | 78 [58] | 4 [24] | |
Multifocal | 57 [42] | 13 [76] | |
Bilobar involvement | 41 [30] | 12 [71] | 0.001* |
AFP | 0.002* | ||
<400 ng/mL | 101 [75] | 6 [35] | |
≥400 ng/mL | 33 [24] | 11 [65] | |
Invasion of major branch of portal or hepatic vein | 21 [16] | 5 [29] | 0.277 |
Data in median [range] or number of patients [percent] or otherwise stated. *, statistically significant. ICG, indocyanine green retention rate at 15 minutes after injection; AFP, alpha-fetoprotein.